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Nzbget issue was a PEBKAC error. I didn't have a category specified. Once I specified a category, I was able to download. Still unable to get nextcloud to work in 5.069 stable & latest beta. Uninstalled plexguide and reinstalled 5.066 and was able to go through initial nextcloud config. I was able to replicate this in a VM as well.
Not sure if this is a factor
Netstat results from test server that nextcloud doesn't work on.]
[email protected]:/home/teNetstatst# netstat -tulpn
Active Internet connections (only servers)
Proto Recv-Q Send-Q Local Address Foreign Address State PID/Program name
tcp 0 0 0.0.0.0:22 0.0.0.0:* LISTEN 981/sshd
tcp 0 0 127.0.0.1:4645 0.0.0.0:* LISTEN 44575/dockerd
tcp 0 0 127.0.0.1:3306 0.0.0.0:* LISTEN 44575/dockerd
tcp6 0 0 :::22 :::* LISTEN 981/sshd
tcp6 0 0 :::9000 :::* LISTEN 44575/dockerd
udp 0 0 0.0.0.0:68 0.0.0.0:* 952/dhclient